Q Write IUPAC code ..

Ans.            IUPAC codes

(i)                 G or c       -                       ‘S’

(ii)               A or T      -                       ‘W’

(iii)             A or C      -                       ‘M’

(iv)             C or T      -                       ‘H’

(v)               A or G     -                       ‘R’

Types of genomics

 There are two main types of genomics.

(i)   Structural genomics – This type of genomics mainly deals with high. Throughput DNA sequencing

      followed by assembly, organization and management of DNA sequences. It represents initial phase of

      genome analysis which involves the construction of high – resolution genetic, physical or transcripts

      map of the organize.  

(ii)Functional genomics – It represents the functional aspect of genome analysis and deals with the reconstruction of the genome to determine the biological function of gene and gene interaction.

Q. What is genomics?

Ans. Genomics – The term genomics was coined in 1986 by Thomas Roderick describe the scientific discipline of mapping, sequencing and analyzing genomes. Genomics is the branch of biotech that deals with the complete study of genomics.

Q. What is proteomics?

Ans. Definition –   The large scale characterization of the entire protein complement of cells, tissues and organism is called as Proteomics. It mainly deals with the studies of protein – protein, interaction, protein function and protein localization.

Q. What is the consequence if a protein is incorrectly folded?

  Ans. Protein are the polymers of amino acids and find expression and product of a gene. Any deformity gene  results in deformity of protein and finally to the host metabolism resulting in to a disease.Proteins that are folded incorrectly cause disease like mad cow disease. These protein are c/a prions. These proteins can cause normal protein to turn diseased resulting into alteration of protein structure. 

Some Coments of Plasmid.

The plasmid has 196 genes that code for 195 proteins. There is no one structural RNA. The plasmid is 206,479 nucleotides long, the GC content is 56% and 81% of the material is coding genes. There are no pseudogenes

What is Agrobacterium ?

 Ans. Agrobacterium is a genus of Gram-negative bacteria  that uses horizontal gene transfer to cause tumors in plants.

 Agrobacterium tumefaciens is a member of the family Rhizobiaceae